What gene makes orange cats orange? Scientists figured it out

Scientists have long been intrigued by the vibrant orange hue of some domestic cats, and recent research has shed light on this captivating genetic trait. Two new studies have identified that the characteristic orange fur is primarily due to a specific DNA deletion on the X chromosome. This breakthrough discovery enhances our understanding of feline genetics and the role of chromosomes in determining fur color. The studies, conducted independently, utilized advanced genetic sequencing to pinpoint the precise deletion responsible for the orange coloration. This genetic anomaly impacts the production of pheomelanin, the pigment responsible for red and yellow hues, leading to the distinct orange shade seen in cats. Interestingly, because the gene is located on the X chromosome, male cats, with their single X chromosome, are more commonly orange than females, who require the deletion on both of their X chromosomes to display the trait. These findings not only decode the mystery behind orange cats but also contribute to broader genetic research, offering insights into how similar mechanisms might influence pigmentation in other species. The studies underscore the complexity of genetic inheritance and open new avenues for exploring how genetic variations can lead to diverse physical traits in animals. As researchers continue to unravel genetic codes, the vibrant world of feline fur patterns becomes a little less mysterious yet infinitely more fascinating.

— Authored by Next24 Live